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Pharmaceutics | Free Full-Text | Identification of Autophagy as a Functional Target Suitable for the Pharmacological Treatment of Mitochondrial Membrane Protein-Associated Neurodegeneration (MPAN) In Vitro
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Dominant mitochondrial membrane protein-associated neurodegeneration (MPAN) variants cluster within a specific C19orf12 isoform - ScienceDirect
![Frontiers | Mutations of C19orf12, coding for a transmembrane glycine zipper containing mitochondrial protein, cause mis-localization of the protein, inability to respond to oxidative stress and increased mitochondrial Ca2+ Frontiers | Mutations of C19orf12, coding for a transmembrane glycine zipper containing mitochondrial protein, cause mis-localization of the protein, inability to respond to oxidative stress and increased mitochondrial Ca2+](https://www.frontiersin.org/files/Articles/133023/fgene-06-00185-HTML/image_m/fgene-06-00185-g010.jpg)
Frontiers | Mutations of C19orf12, coding for a transmembrane glycine zipper containing mitochondrial protein, cause mis-localization of the protein, inability to respond to oxidative stress and increased mitochondrial Ca2+
![Review: Insights into molecular mechanisms of disease in neurodegeneration with brain iron accumulation: unifying theories - Arber - 2016 - Neuropathology and Applied Neurobiology - Wiley Online Library Review: Insights into molecular mechanisms of disease in neurodegeneration with brain iron accumulation: unifying theories - Arber - 2016 - Neuropathology and Applied Neurobiology - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/c9b328d8-d68c-451f-955a-2994068340a8/nan12242-fig-0002-m.jpg)
Review: Insights into molecular mechanisms of disease in neurodegeneration with brain iron accumulation: unifying theories - Arber - 2016 - Neuropathology and Applied Neurobiology - Wiley Online Library
![PDF] Mutations of C19orf12, coding for a transmembrane glycine zipper containing mitochondrial protein, cause mis-localization of the protein, inability to respond to oxidative stress and increased mitochondrial Ca2+ | Semantic Scholar PDF] Mutations of C19orf12, coding for a transmembrane glycine zipper containing mitochondrial protein, cause mis-localization of the protein, inability to respond to oxidative stress and increased mitochondrial Ca2+ | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/dd2ecb2012d86f9d3853c6aef367791e936d0787/11-Figure9-1.png)
PDF] Mutations of C19orf12, coding for a transmembrane glycine zipper containing mitochondrial protein, cause mis-localization of the protein, inability to respond to oxidative stress and increased mitochondrial Ca2+ | Semantic Scholar
![Frontiers | The Downregulation of c19orf12 Negatively Affects Neuronal and Musculature Development in Zebrafish Embryos Frontiers | The Downregulation of c19orf12 Negatively Affects Neuronal and Musculature Development in Zebrafish Embryos](https://www.frontiersin.org/files/Articles/596069/fcell-08-596069-HTML/image_m/fcell-08-596069-g001.jpg)
Frontiers | The Downregulation of c19orf12 Negatively Affects Neuronal and Musculature Development in Zebrafish Embryos
Alignment of the fly C19orf12 orthologs (CG3740, CG11671) with human... | Download Scientific Diagram
![SPG43 and ALS-like syndrome in the same family due to compound heterozygous mutations of the C19orf12 gene: a case description and brief review | SpringerLink SPG43 and ALS-like syndrome in the same family due to compound heterozygous mutations of the C19orf12 gene: a case description and brief review | SpringerLink](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs10048-020-00631-4/MediaObjects/10048_2020_631_Fig1_HTML.png)
SPG43 and ALS-like syndrome in the same family due to compound heterozygous mutations of the C19orf12 gene: a case description and brief review | SpringerLink
![C19orf12 ablation causes ferroptosis in mitochondrial membrane protein-associated with neurodegeneration - ScienceDirect C19orf12 ablation causes ferroptosis in mitochondrial membrane protein-associated with neurodegeneration - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0891584922000594-ga1.jpg)
C19orf12 ablation causes ferroptosis in mitochondrial membrane protein-associated with neurodegeneration - ScienceDirect
Brain iron and metabolic abnormalities in C19orf12 mutation carriers: A 7.0 tesla MRI study in mitochondrial membrane protein-associated neurodegeneration. - Munich Cluster for Systems Neurology - LMU Munich
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C19orf12 gene mutations in patients with neurodegeneration with brain iron accumulation - ScienceDirect
![Neurodegeneration of diPLA2-VIA −/− flies is rescued by MPAN-associated... | Download Scientific Diagram Neurodegeneration of diPLA2-VIA −/− flies is rescued by MPAN-associated... | Download Scientific Diagram](https://www.researchgate.net/publication/336011002/figure/fig2/AS:807692817952770@1569580382645/Neurodegeneration-of-diPLA2-VIA--flies-is-rescued-by-MPAN-associated-C19orf12-A.jpg)
Neurodegeneration of diPLA2-VIA −/− flies is rescued by MPAN-associated... | Download Scientific Diagram
![PDF] Absence of an orphan mitochondrial protein, c19orf12, causes a distinct clinical subtype of neurodegeneration with brain iron accumulation. | Semantic Scholar PDF] Absence of an orphan mitochondrial protein, c19orf12, causes a distinct clinical subtype of neurodegeneration with brain iron accumulation. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/8f4b65f35621e9f879833a58183ba96b06f5ec7f/4-Figure2-1.png)
PDF] Absence of an orphan mitochondrial protein, c19orf12, causes a distinct clinical subtype of neurodegeneration with brain iron accumulation. | Semantic Scholar
![Frontiers | Mutations of C19orf12, coding for a transmembrane glycine zipper containing mitochondrial protein, cause mis-localization of the protein, inability to respond to oxidative stress and increased mitochondrial Ca2+ Frontiers | Mutations of C19orf12, coding for a transmembrane glycine zipper containing mitochondrial protein, cause mis-localization of the protein, inability to respond to oxidative stress and increased mitochondrial Ca2+](https://www.frontiersin.org/files/Articles/133023/fgene-06-00185-HTML/image_m/fgene-06-00185-g002.jpg)
Frontiers | Mutations of C19orf12, coding for a transmembrane glycine zipper containing mitochondrial protein, cause mis-localization of the protein, inability to respond to oxidative stress and increased mitochondrial Ca2+
![Nazo, the Drosophila homolog of the NBIA-mutated protein – c19orf12, is required for triglyceride homeostasis | bioRxiv Nazo, the Drosophila homolog of the NBIA-mutated protein – c19orf12, is required for triglyceride homeostasis | bioRxiv](https://www.biorxiv.org/content/biorxiv/early/2022/09/30/2022.09.29.510106/F4.large.jpg)
Nazo, the Drosophila homolog of the NBIA-mutated protein – c19orf12, is required for triglyceride homeostasis | bioRxiv
![LC3 puncta formation in C19orf12 D18G/L132Q fibroblasts after 24 h of... | Download Scientific Diagram LC3 puncta formation in C19orf12 D18G/L132Q fibroblasts after 24 h of... | Download Scientific Diagram](https://www.researchgate.net/publication/367108345/figure/fig2/AS:11431281112935442@1673616549030/LC3-puncta-formation-in-C19orf12-D18G-L132Q-fibroblasts-after-24-h-of-CCCP-treatment.png)